Fig. 2

Scheme of the functional connectivity network construction. The timeseries was extracted for each ROI, and Pearson’s correlation between the ROI timeseries was subsequently calculated to define the connection (matrix element) between the ROIs. By calculating this quantity for each pair of ROIs, a functional connectivity (FC) matrix for each patient was obtained. Finally, the FC matrices were proportionally thresholded in the range of 5–50% of the network density.