Fig. 5 | Scientific Reports

Fig. 5

From: Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA

Fig. 5

PMX → MS275 mediated overall downregulation of known DNA repair proteins (Supplementary Table S2). Graphic representation of DNA repair proteins significantly affected (> + / − 1.5-fold, p < 0.05) by at least one of the treatments (MS275, PMX or PMX → MS275). Proteins present in both nuclei and mitochondria are denoted with a blue asterisk, whereas those only found in mitochondria are denoted with a red asterisk.

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