Fig. 7

Evolution of intrinsic disorder in the structural domains of proteins. (a) Mean disorder in domains present in superkingdoms and viruses. (b) Evolutionary history of domains corresponding to the three disorder groups. (c) Evolutionary history of domains in cells and in cells and viruses. (d) Number of domains expressed in absolute and cumulative numbers that appear in the bins of the evolutionary timeline. (e) Distribution of disorder along the evolutionary chronology of domains grouped by types of disorder. Note that families with high disorder appear in the third time of origin (nd) bin of the chronology. (f) Relationship between mean disorder and mean length of domains shared only among cells and those shared between viruses and cells. Box plots describe domain length distributions.