Fig. 1 | Scientific Reports

Fig. 1

From: Polystyrene microplastics induce liver fibrosis and lipid deposition in mice through three hub genes revealed by the RNA-seq

Fig. 1

Physiological characteristics and liver histology changes after PS-NMPs exposure (80 nm, 0.5 µm, and 5 µm). The levels of liver weight (A), body weight (B), liver/body weight index (liver weight/body weight (%) (C), ALT (D), and AST (E) at 12 weeks after different diameters of PS-NMPs exposure (n = 5–8). (F) Representative images of mice livers by HE staining (left panel) and quantification of histological changes in liver exposure to different diameters of PS-NMPs (right panel) (n = 8). Red arrow indicated binuclear cells, red triangle indicated hepatocellular vacuolar deformation and edema, black arrow indicated infiltration of inflammatory cells, and black triangle indicated irregularly arranged hepatic cords. Scale bar, 100 µm. *p < 0.05, **p < 0.01, ***p < 0.001.

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