Table 4 Linear regression analysis in crude and adjusted models investigating the association between hematological indices and generalized anxiety disorder according to sex.

From: The association between major depressive disorder and generalized anxiety disorder with hematological indices in the Rafsanjan youth cohort study

Variables

Generalized anxiety disorder

Crude model

P-value

Adjusted model 1

P-value

Adjusted model 2

P-value

WBC

Males

0.17(−0.21, 0.55)

0.38

0.135(−0.251, 0.522)

0.492

0.11(−0.276, 0.496)

0.577

Females

−0.21(−0.51, 0.08)

0.16

−0.203(−0.493, 0.087)

0.17

−0.20(−0.49, 0.09)

0.18

RBC

Males

−0.03(−0.13, 0.08)

0.60

−0.004(−0.107, 0.1)

0.212

0.01(−0.09, 0.14)

0.844

Females

0.03(−0.04. 0.10)

0.42

0.04(−0.26, 0.112)

0.211

0.041(−0.028, 0.114)

0.24

HGB

Males

−0.04(−0.22, 0.31)

0.74

0.116(−0.247, 0.279)

0.906

0.03(−0.24, 0.303)

0.751

Females

0.10(− 0.08, 0.28)

0.26

0.148(− 0.31, 0.327)

0.104

0.15(− 0.03, 0.32)

0.11

HCT

Males

−0.04(−0.74, 0.65)

0.90

0.117(−0.583, 0.816)

0.744

0.25(−0.473, 0.903)

0.547

Females

0.38(−0.87, 0.10)

0.118

0.504(0.24, 0.985)

0.04

0.494(0.114, 0.974)

0.044

MCV

Males

0.32(−0.87, 1.50)

0.60

0.269(−0.929, 1.466)

0.66

0.231(−0.97, 1.42)

0.706

Females

0.32(−0.67, 1.31)

0.52

0.33(−0.66, 1.32)

0.513

0.34(−0.651, 1.33)

0.501

MCH

Males

0.06(−0.43, 0.05)

0.82

0.031(−0.468, 0.53)

0.902

−0.033(−0.51, 0.49)

0.902

Females

0.07(−0.33, 0.46)

0.75

0.078(−0.321, 0497)

0.691

−0.08(−0.32, 0.48)

0.69

MCHC

Males

−0.05(−0.24, 0.15)

0.63

−0.33(−0.229, 0.162)

0.737

−0.047(−0.25, 0.15)

0.664

Females

−0.05(–0.19, 0.09)

0.47

00.039(−0.197, 1.099)

0.584

−0.038(−0.018, 0.099)

0.584

RDW

Males

0.001(−0.12, 0.12)

0.98

−0.015(−0.133, 0.106)

0.807

−0.01(−0.13, 0.106)

0.854

Females

−0.13(−0.26, 0.003)

0.06

−0.143(−0.274, −0.012)

0.032

−0.15(−0.277, −0.015)

0.029

PLT

Males

4.83(−5.77, 15.43)

0.37

6.794(−3.742, 17.452)

0.211

6.86(−3.86, 17.58)

0.198

Females

1.03(−7.75, 9.82)

0.82

2.267(−0.493, 11.027)

0.612

2.29(−6.492, 11.072)

0.609

N/L(NLR)

Males

0.22(0.09, 0.34)

0.001

0.208(0.282, 0.334)

0.001

0.22(0.09, 0.34)

0.001

Females

−0.06(−0.15, 0.04)

0.23

−0.81(−0.184, 0.012)

0.086

−0.08(−0.17, 0.01)

0.1

N

Males

2.79(0.07, 5.51)

0.04

2.35(−0.451, 5.102)

0.094

2.69(−0.08, 5.46)

0.06

Females

−0.82(−2.82, 1.19)

0.42

−1.313(−3.431, 0.575)

0.164

−1.34(−3.36, 0.652)

0.187

L

Males

−2.79(−5.33, −0.26)

0.03

−2.454(−5.22, 0.114)

0.061

−2.71(−5.39, −0.136)

0.039

Females

0.81(−1.06, 2.68)

0.40

1.357(−0.498, 3.212)

0.152

1.292(−0.54, 3.18)

0.173

M

Males

−0.03(−0.41, 0.36)

0.89

0.062(−0.327, 0.451)

0.753

0.067(−0.324, 0.45)

0.737

Females

0.07(−0.20, 0.33)

0.62

0.122(−0.137, 0.381)

0.357

0.15(−0.14, 0.38)

0.386

MPV

Males

−0.01(−0.14, 0.12)

0.88

−0.024(−0.184, 0.11)

0.726

−0.02(−0.15, 0.0111)

0.726

Females

0.1 (0.006, 0.20)

0.045

0.101(0.002, 0.095)

0.045

0.102(0.003, 0.201)

0.045

PCT

Males

0.004(−0.004, 0.01)

0.39

0.005(−0.003, 0.013)

0.246

0.005(−0.003, 0.013)

0.23

Females

0.004(−0.003, 0.01)

0.27

0.005(−0.002, 0.011)

0.171

0.005(−0.002, 0.011)

0.16

PDW

Males

−0.03(−0.003, 0.05)

0.38

−0.197(−0.276, 0.006)

0.212

−0.103(−0.27, 0.07)

0.234

Females

−0.06(−0.18, 0.07)

0.37

−0.065(−0.187, 0.057)

0.296

−0.06 (−0.18, 0.058)

0.303

  1. The Crud model was not adjusted.
  2. Model 1 included age, education, physical activity, body mass index (BMI). histories of arteritis rheumatoid, diabetes and hypertension. Adjusted model 2 included all variables in model 1 and additionally included smoking, alcohol consumption, opium use. Significant values are in bold.
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