Fig. 2
From: Morphological and functional analysis of colorectal cancer cell lines in 2D and 3D culture models
Immunocytochemical images of E-cadherin and vimentin in 2D and 3D cultured colorectal adenocarcinoma (CRAC) cells. E-cadherin and vimentin expression levels in five human CRC cell lines were determined using immunocytochemical analysis. In 2D cultures, E-cadherin was weakly expressed in the cytoplasm of DLD-1, CACO-2, HCT-15, and SW480 cells, but in 3D cultures it was prominently localized to the plasma membrane in these cells. Vimentin was localized in SW480 and COLO-320 cells cultured in 2D and 3D cultures. Scale bar = 50 μm.
