Table 5 Activity inhibition of α-amylase and α-glucosidase by Extract, ZnO@MgO NPs, and acarbose. The data shows means ± standard error (n = 3). According to Tukey’s test (HSD), significant differences (P ≤ 0.05) are indicated by different lowercase letters in the same species within a column.
Concentration (µg/mL) | α-Amylase inhibition % | HSD | α-Glucosidase inhibition % | HSD | ||||
|---|---|---|---|---|---|---|---|---|
Acarbose | Extract | ZnO@MgO NPs | Acarbose | Extract | ZnO@MgO NPs | |||
1000 | 87.9 ± 1.32b | 78.7 ± 2.15c | 95.0 ± 1.69a | 3.32 | 89.8 ± 1.10a | 75.1 ± 0.89c | 84.6 ± 1.21b | 3.32 |
500 | 81.7 ± 0.98b | 72.6 ± 0.65c | 90.6 ± 0.78a | 3.21 | 84.0 ± 0.56a | 69.3 ± 0.78c | 78.5 ± 0.89b | 2.21 |
250 | 75.1 ± 1.65b | 66.1 ± 1.89c | 84.0 ± 0.87a | 2.87 | 78.4 ± 0.25a | 63.2 ± 0.36c | 72.6 ± 0.42b | 1.23 |
125 | 68.7 ± 0.98b | 59.9 ± 1.20c | 78.2 ± 0.68a | 2.21 | 73.0 ± 0.15a | 57.8 ± 0.36c | 67.4 ± 0.21b | 0.96 |
62.50 | 62.3 ± 1.02b | 53.7 ± 0.89c | 71.8 ± 0.32a | 3.32 | 67.1 ± 0.85a | 51.8 ± 0.36c | 61.7 ± 0.58b | 2.10 |
31.25 | 56.3 ± 0.87b | 47.5 ± 1.02c | 65.5 ± 0.68a | 2.23 | 61.6 ± 1.02a | 45.6 ± 0.95c | 55.2 ± 0.80b | 3.21 |
15.63 | 49.8 ± 0.25b | 40.4 ± 0.32c | 58.6 ± 0.58a | 1.21 | 56.6 ± 0.52a | 39.6 ± 0.45c | 48.2 ± 0.42b | 1.35 |
7.81 | 42.9 ± 0.09b | 34.4 ± 0.25c | 47.1 ± 0.16a | 0.65 | 50.3 ± 0.25a | 34.2 ± 0.36c | 44.6 ± 0.19b | 0.85 |
3.90 | 36.2 ± 0.89b | 27.6 ± 1.03c | 40.6 ± 0.75a | 2.36 | 44.0 ± 1.09a | 28.4 ± 0.87c | 38.8 ± 0.65b | 2.32 |
1.95 | 30.0 ± 1.05b | 21.4 ± 1.16c | 34.2 ± 0.69a | 3.26 | 38.1 ± 0.82a | 23.2 ± 1.02c | 33.6 ± 0.86b | 2.48 |
0.00 | 0.0 ± 0.0 | 0.0 ± 0.0c | 0.0 ± 0.0 | 00 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 00 |
IC50 µg/mL | 117.02 ± 0.56b | 260.05 ± 1.09a | 6.5 ± 0.36c | 6.32 | 22.15 ± 0.76c | 291.22 ± 60a | 120.76 ± 1.19b | 4.36 |
