Fig. 4
Ca2+ mobilization assay responses in wild-type CaSR and mutants. (a, b) EC50 values were calculated from the concentration–response curves (Fig. 3 and Supplementary Fig. S6). Data are means from three independent experiments (n = 3). (c) Emax values (% of wild-type values) were calculated from the concentration–response curves (Fig. 3 and Supplementary Fig. S6). Data are shown as mean ± s.e.m. from three independent experiments (n = 3). The horizonal dotted line shows Emax of the wild type. CaSR calcium-sensing receptor, Emax maximum response, γ-EV γ-glutamyl-valine, γ-EVG γ-glutamyl-valyl-glycine, WT wild type, ND not detected.
