Table 3 Results of the sensitivity analysis of the reverse mendelian randomization analysis with GC as exposure.

From: Mendelian randomization analysis of plasma proteins reveals potential novel tumor markers for gastric cancer

Outcome

Heterogeneity analysis

Pleiotropy analysis

Inverse variance weighted

MR Egger

MR Egger

MR PRESSO global test

Q

Q_df

Q_pval

Q

Q_df

Q_pval

Egger_intercept

se

pval

pval

NFE2L1

12.1007

7

0.0973

8.0219

6

0.2365

-0.0188

0.0108

0.1313

0.0830

ADH7

11.6433

7

0.1129

6.1575

6

0.4058

-0.0222

0.0096

0.0601

0.1220

FAM3D

2.6798

7

0.9130

1.8055

6

0.9367

-0.0087

0.0093

0.3859

0.8980

PDE5A

6.2716

7

0.5084

4.1989

6

0.6498

-0.0138

0.0096

0.2000

0.4390

MAP1LC3A

12.6129

7

0.0821

7.9496

6

0.2418

-0.0216

0.0115

0.1098

0.0820

PMM2

9.1661

7

0.2409

6.8849

6

0.3316

-0.0147

0.0104

0.2082

0.2110

GLUL

10.7245

7

0.1511

6.9253

6

0.3278

-0.0182

0.0101

0.1196

0.1280

MAFG

5.2824

7

0.6255

3.3473

6

0.7642

-0.0132

0.0095

0.2136

0.5990

PGLYRP1

6.1423

7

0.5232

6.0812

6

0.4142

-0.0024

0.0098

0.8142

0.6010

L1CAM

3.9475

7

0.7858

3.2654

6

0.7749

-0.0082

0.0100

0.4405

0.8110

CHST15

6.3373

7

0.5010

4.5598

6

0.6014

-0.0128

0.0096

0.2308

0.5190

FTMT

3.7138

7

0.8121

3.4073

6

0.7563

0.0052

0.0093

0.5999

0.8160

FAM3B

6.1797

7

0.5189

6.1785

6

0.4035

-0.0003

0.0102

0.9742

0.4890

ABO

4.0811

7

0.7704

3.9829

6

0.6790

-0.0023

0.0073

0.7647

0.7160

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