Fig. 1 | Scientific Reports

Fig. 1

From: Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice

Fig. 1

Experimental procedures of drug administration and behavioral tests. (a) ICR mice were divided into six groups (n = 10/group): NC, normal control group; SCO, SCO-injected group; EEBC-50, group treated with 50 mg/kg of EEBC and SCO injection; EEBC-100, group treated with 100 mg/kg of EEBC and SCO injection; EEBC-200, group treated with 200 mg/kg of EEBC and SCO injection; PC, group treated with 10 mg/kg of tacrine and SCO injection. EEBC or PC were orally administered daily for 20 days. The passive avoidance task (PAT) and Y-maze test were conducted on the 14th − 16th and 19th day after SCO injection, respectively. Cognitive impairments were induced via SCO injection (1 mg/kg, i.p.) within 1 h after oral administration of EEBC. (b) Changes in body weight were measured every week after EEBC treatment. NC, normal control; SCO, scopolamine; EEBC, ethanol extract from Bauhinia coccinea; PC, positive control (tacrine).

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