Fig. 4 | Scientific Reports

Fig. 4

From: Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice

Fig. 4

Protective effects of EEBC on neuronal damage in scopolamine (SCO)-induced memory deficit mice. Multiple 4-µm paraffin sections of the hippocampus and cortex regions were prepared from the sacrificed mouse brains. (a) Nissl staining was conducted using a cresyl violet solution. Representative photomicrographs are shown at a magnification of 50× for the whole brain (upper) or 200× for CA1 (middle) and cortex (lower); scale bar, 200 μm for the whole brain or 20 μm for CA1 and cortex. (b and c) Bar graphs display the quantitative analysis of Nissl-stained cell bodies in the CA1 (b) and cortex (c). Data are presented as mean ± SEM (n = 3/group). **p < 0.01 or ***p < 0.001 vs. NC group, #p < 0.05, ##p < 0.01, or ###p < 0.001 vs. SCO group. Statistical power exceeded 0.999. NC, normal control; SCO, scopolamine; EEBC, ethanol extract from Bauhinia coccinea; PC, positive control (tacrine); CA, cornu ammonis.

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