Fig. 1

Basepair insertion in Exon 11 of Myt1l Het mice leads to decreased Myt1l expression in the brain. (A) Schematic of basepair insertion in Exon 11 of Myt1l gene (Duplicate G—outlined in red) in Myt1l Het mouse resulting in frameshift and stop-gain mutation. (B) Whole brain Myt1l gene expression normalized to WT mice. Filled circles represent individual animals. T-test, p = 0.027.