Fig. 11

Guide for method selection to estimate connectivity from activity in neural networks. The input to all methods is recorded GT activity data, for which assumptions on the presence or absence of delays and underlying dynamical model need to be made. Also, an initial estimate about the network size and its density should be made. With these inputs and assumptions, we can proceed with a choice of estimation method. For non-linear dynamics and small delays, LCC is the preferred method, whereas DDC is the preferred method for linear dynamics with small/ absent or large delays. For non-linear dynamics with large delays, the thresholded DDC method is preferred.