Table 2 Hepatic proteins most differentially expressed in livers of UGT2B17-deficient individuals.
From: The liver proteome of individuals with a natural UGT2B17 complete deficiency
Uniprot ID | Protein name | Gene name | FC | P | |
|---|---|---|---|---|---|
Higher abundance | Q9UBI1 | COMM domain-containing protein 3 | COMMD3 | 18.7 | 0.017 |
P04839 | Cytochrome b-245 heavy chain | CYBB | 12.8 | 0.004 | |
Q9NUQ8 | ATP-binding cassette sub-family F member 3 | ABCF3 | 11.9 | 0.049 | |
P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | ACAA2 | 11.6 | 0.046 | |
P60903 | Protein S100-A10 | S100A10 | 11.4 | 0.018 | |
P35609 | Alpha-actinin-2 | ACTN2 | 8.6 | 0.005 | |
Q99538 | Legumain | LGMN | 8.5 | 0.023 | |
P30419 | Glycylpeptide N-tetradecanoyltransferase 1 | NMT1 | 7.9 | 0.026 | |
Q96PX9 | Pleckstrin homology domain-containing family G member 4B | PLEKHG4B | 7.6 | 0.009 | |
Q8TCT9 | Minor histocompatibility antigen H13 | HM13 | 7.5 | 0.008 | |
Lower abundance | Q8N339 | Metallothionein-1M | MT1M | − 12.1 | 0.003 |
Q6P1X5 | Transcription initiation factor TFIID subunit 2 | TAF2 | − 8.0 | 0.004 | |
P35557 | Glucokinase | GCK | − 7.8 | 0.044 | |
Q5VTH9 | Dynein axonemal intermediate chain 4 | DNAI4 | − 5.5 | 0.020 | |
P30711 | Glutathione S-transferase theta-1 | GSTT1 | − 5.3 | 0.041 | |
O75884 | Putative hydrolase RBBP9 | RBBP9 | − 5.1 | 0.033 | |
Q5SW79 | Centrosomal protein of 170 kDa | CEP170 | − 4.8 | 0.025 | |
Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | CHCHD2 | − 4.6 | 0.049 | |
Q9UI12 | V-type proton ATPase subunit H | ATP6V1H | − 3.8 | 0.045 | |
P04181 | Ornithine aminotransferase, mitochondrial; | OAT | − 3.6 | 0.043 |
