Fig. 2
From: GTPBP2 in-frame deletion in canine model with non-syndromic progressive retinal atrophy
Mapping. (a) Family tree of the affected dogs. Males in squares, females in circles, affected in blue. Obligate carriers (and unaffected sibling later identified as carriers) as half-filled shapes. Autosomal recessive inheritance mechanism was suspected. The whole family was genotyped on canine SNP chip, whole-genome sequenced dogs are marked with red asterisk. (b) Homozygosity mapping of the three cases, compared against the three available unaffected siblings and two parents was carried out. The homozygous regions shared by all the cases and exclusive to them compared to the controls are marked in red (37 Mb region in CFA12 marked with an asterisk).
