Fig. 2

Cellular communication and ligand analysis. (A) Directionality and quantity of communication between cells; (B) Directionality and intensity of communication between cells; (C) Ligand analysis with fibroblasts as the source across different cell types; (D) Ligand analysis with fibroblasts as the target across different cell types; (E) Identification of signals that contribute most significantly to the output or input of various cell groups; (F–J) Intercellular communication diagram of a portion of the signaling network.