Fig. 7

Mendelian randomization analysis of model genes and CRC. (A) Scatterplot illustrating the results of five methods. The abscissa represents the impact of SNP on the gene PLOD3, while the ordinate represents the impact of SNP on CRC. The dots in the plot represent SNPs, and the crosshairs indicate the fluctuation range of the effect size. (B) Results of the Mendelian randomization analysis utilizing the five methods.