Table 3 Concentrations of total fatty acids and ratios in Hashimoto’s disease and control groups (μmol/L).

From: Identifying the metabolic profile of Hashimoto’s thyroiditis from the METHAP clinical study

 

Hashimoto

Control

p value

Mean ± SD

Median

Mean ± SD

Median

C183n3

43.12 + 19.79

43.21

47.63 + 23.82

44.35

0.248

C203n3

2.07 + 1.81

1.14

1.69 + 1.42

1.00

0.303

C205n3

60.05 + 34.63

52.42

51.88 + 31.71

44.21

0.138

C226n3

140.52 + 59.95

138.81

140.4 + 57.21

136.38

0.928

C183n6

38.47 + 30.89

30.21

39.67 + 26.27

38.14

0.475

C182n6

2514.15 + 1084.72

2569.38

2707.8 + 1009.37

2747.88

0.395

C204n6

475.82 + 173.61

465.02

427.21 + 137.38

402.98

0.094

C203n6 (b)

113.9 + 42.99

113.67

94.08 + 43.88

87.29

0.004

C151

30.02 + 25.51

24.23

24.73 + 16.36

20.13

0.250

C161n7 (a)

125.82 + 70.07

113.21

88.13 + 51.11

71.75

< 0.0001

C181n9cis

1986.44 + 800.87

1844.4

2017.49 + 750.24

1993.50

0.684

C201n9

19.36 + 11.66

18.89

17 + 11.05

17.03

0.273

C22:1n9

1.69 + 1.72

1

1.27 + 0.6

1.00

0.637

C241n9

65.18 + 22.14

62.21

59.74 + 18.66

56.03

0.193

C120

2.66 + 2.37

2

3.56 + 5.64

2.00

0.957

C140

63.05 + 39.44

53.77

49.53 + 33.85

40.18

0.014

C150

6.85 + 3.16

6.26

7.39 + 5.41

6.08

0.678

C160 (a)

2280.58 + 631.46

2169.33

1867.6 + 467.6

1796.59

< 0.0001

C180

609.97 + 120.62

598.66

558.89 + 155.6

533.39

0.004

C200

14.36 + 6.65

13.71

13.97 + 5.06

14.13

0.867

C220

38.34 + 22.56

34.65

36.37 + 11.57

33.81

0.764

C240

53.93 + 20.84

56.83

50.9 + 17.34

49.12

0.351

C141 (a)

2.88 + 2.01

2

2.21 + 2.35

1.72

< 0.0001

C204n6/C203n6 ratio

4.53 + 1.77

4.29

5.09 + 1.8

4.87

0.080

C204n6/C205n3 ratio

10.85 + 10.49

7.98

11.31 + 10.06

9.84

0.434

C182n6/C183n6 ratio

88.53 + 54.49

70.45

102.33 + 92.18

78.45

0.648

C141/C140 ratio

0.06 + 0.06

0.04

0.04 + 0.02

0.04

0.462

C161n7/C160 ratio (b)

0.05 + 0.02

0.06

0.05 + 0.02

0.04

0.015

C181n9cis/C180 ratio

3.29 + 1.23

3.13

3.75 + 1.49

3.40

0.088

SFA (a)

3069.74 + 769.82

2912.72

2588.21 + 644.86

2427.48

< 0.0001

PUFA

3388.11 + 1215.04

3502.74

3510.36 + 1118.44

3564.29

0.599

TOTAL

8689.24 + 2315.99

8560.79

8309.14 + 2228.56

8186.89

0.290

SFA/TOTAL ratio

0.36 + 0.09

0.34

0.32 + 0.07

0.30

0.003

MUFA

2231.39 + 862.69

2057.31

2210.57 + 785.56

2166.39

0.996

Omega 6/3 ratio

13.84 + 6.61

12.68

14.44 + 5.6

12.94

0.431

  1. Non-parametric Mann–Whitney test, Ho: The distribution of characteristics is the same between the groups. Bonferroni correction was applied with a p critical value at 0.05/23; statistically significant variables were depicted in bold (a); Statistically significant based on false discovery rate in bold (b) for a = 0.1. SFA saturated fatty acids, PUFA polyunsaturated fatty acids, MUFA monounsaturated fatty acids, TOTAL total fatty acids.
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