Fig. 3 | Scientific Reports

Fig. 3

From: OM85 ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting Notch expression and modulating the IFN-γ/IL-4 ratio

Fig. 3

OM85 reduces BLM-induced lung cell accumulation in mice. In IPF-induced pulmonary lavage, there is an increase in the total number of cells, macrophages, lymphocytes, and neutrophils. Administration of OM85 decreases the numbers of these four cell types, alleviating the accumulation of inflammation in the lungs. After assessing the sample distribution’s normality and calculating the sample’s standard deviation (SD), ordinary ANOVA tests were conducted for total cell count and macrophages, while one-way Welch ANOVA tests were used for lymphocytes and neutrophils. Data represent means ± SD of 6 mice. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, and ns for P > 0.05.

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