Fig. 7 | Scientific Reports

Fig. 7

From: OM85 ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting Notch expression and modulating the IFN-γ/IL-4 ratio

Fig. 7

OM85 reduced the expression of collagen I in C57 lung tissue and lowered the hydroxyproline content of lung homogenates in C57 induced by BLM. Representative histology of immunohistochemistry for type I collagen in lung tissue at 20X magnification from four groups (A), the analysis of the optical density (OD) of collagen I (B), and the analysis of hydroxyproline content in lung homogenates (C). After assessing the normality of the sample distribution and calculating the standard deviation (SD) of the sample, ordinary ANOVA tests were conducted (B) and one-way Welch ANOVA tests were conducted (C). Data represent means ± SD of 6 mice (B). Data represent means ± SD of 10 mice (C). ** P < 0.01, **** P < 0.0001, and ns for P > 0.05.

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