Fig. 8 | Scientific Reports

Fig. 8

From: OM85 ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting Notch expression and modulating the IFN-γ/IL-4 ratio

Fig. 8

OM85 mitigates the decline of IPF-related proteins induced by BLM. Panel A represents the Western blot experiments for various proteins. Panel B analyzes Notch1 protein levels, Panel C for Hes1, Panel D for collagen I, Panel E for collagen III, Panel F for α-SMA, Panel G for fibronectin, and Panel H for P21. After assessing normality and calculating the standard deviation (SD) of the sample, ordinary ANOVA tests were performed for Notch1 and α-SMA, whereas one-way Welch ANOVA tests were utilized for Hes1, collagen I, collagen III, fibronectin, and P21. Data represent means ± SD for 10 mice. **P < 0.01, ***P < 0.001, ****P < 0.0001, and ns for P > 0.05.

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