Fig. 6 | Scientific Reports

Fig. 6

From: Knockdown of CCNB2 inhibits the tumorigenesis of gastric cancer by regulation of the PI3K/Akt pathway

Fig. 6

CCNB2 promotes the proliferation and migration of GC cells through RHBDL2. (A) Co-immunoprecipitation assays demonstrate the interaction between CCNB2 and RHBDL2 in MKN-45 cells. (B-C) The expression levels of EMT-related proteins and components of the PI3K/AKT signaling pathway in MKN-45 cells transfected with RHBDL2 following CCNB2 knockdown were analyzed via Western blotting. (D-F)The inhibitory effects of CCNB2 knockdown on MKN-45 cell proliferation and migration can be reversed by RHBDL2 overexpression. Data are presented as mean ± SD.

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