Fig. 1 | Scientific Reports

Fig. 1

From: Increased activation of the WNT pathway in brain tissue from patients with cortical dysplasia type IIb

Fig. 1

Gene expression analysis of samples from patients with FCD: (A) Relative expression analysis using the 2-ΔΔCt calculation showing increased expression of the LRP5, LRP6, DKK1, and DVL1 genes in dysplastic cortical tissue. (B) Heatmap constructed using 2-ΔCt values showing differences in the expression profiles of samples from the FCD group compared to the control group. Histological sections stained with hematoxylin and eosin of cortical tissue samples from a control patient (C) and an FCD patient (D), showing the characterization and presence of balloon cells (arrows) in the FCD tissue. The Student’s t test was used to determine statistical significance. Error bars represent SEM.

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