Fig. 5

Correlation between ADAM12 expression and MATH, TMB, and MSI in various cancer types. Spearman correlation analysis of ADAM12 expression with MATH (A), MSI (B), and TMB (C) in the TCGA datasets. The horizontal axis represents the correlation coefficient, while the vertical axis represents different tumor types. The size of the dots reflects the magnitude of the correlation coefficient, and colors indicate the significance of the p-value. The deeper the blue, the smaller the p-value. (D) Correlation analysis between ADAM12 gene expression and MATH in TCGA-GBMLGG/LGG/GBM. (E) Correlation analysis between ADAM12 gene expression and MSI in TCGA-GBMLGG/LGG/GBM. (F) Correlation analysis between ADAM12 gene expression and TMB in TCGA-GBMLGG/LGG/GBM. The abscissa represents gene expression distribution, and the ordinate represents MATH/TMB/MSI score distribution. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.