Table 2 Baseline characteristics of participants in the ADNI by their cognitive status.
Baseline characters | Cognitively normal | Mild cognitive impairment |
|---|---|---|
n | 248 | 437 |
Age (years) | ||
Mean (SD) | 75 (6) | 72 (7) |
Range | 60–90 | 55–91 |
Male (%) | 128 (51.6) | 262 (60.0) |
Education (years) | ||
Mean (SD) | 16.4 (2.7) | 16.0 (2.9) |
Range | 6–20 | 6–20 |
BMI (kg/m2) | ||
Mean (SD) | 25.7 (4.0) | 26.7 (4.9) |
Range | 18.4–45.8 | 17.9–50.9 |
Ever smokers (%) | 95 (38.3) | 163 (37.3) |
APOE4 risk allele frequency, % | 15.3 | 27.4 |
APOE4 risk allele (%) | ||
Non carrier | 178 (71.8) | 236 (54.0) |
Carrier | 70 (28.2) | 201 (46.0) |
Mini Mental State Exam, MMSE | ||
Mean (SD) | 29.06 (1.17) | 27.93 (1.66) |
Range | 24–30 | 23–30 |
Alzheimer Disease Assessment Scale 11, ADAS 11 | ||
Mean (SD) | 5.81 (2.90) | 9.56 (4.34) |
Range | 0–19 | 1–26 |
Alzheimer Disease Assessment Scale 13, ADAS 13 | ||
Mean (SD) | 9.13 (4.25) | 15.35 (6.66) |
Range | 0–24 | 2–36 |
Montreal Cognitive Assessment, MoCA | ||
Mean (SD) | 25.66 (2.26) | 23.63 (2.99) |
Range | 19–30 | 15–30 |
Functional Assessment Questionnaire, FAQ | ||
Mean (SD) | 0.17 (0.67) | 2.86 (3.91) |
Range | 0–6 | 0–22 |
ADNI memory summary score, ADNI_MEM | ||
Mean (SD) | 1.04 (0.56) | 0.30 (0.67) |
Range | – 0.3 to 3.1 | – 1.5 to 2.2 |
ADNI executive function score, ADNI_EF | ||
Mean (SD) | 0.82 (0.76) | 0.37 (0.85) |
Range | – 1.0 to 3.0 | – 2.0 to 3.0 |
ADNI language summary score, ANDI_LAN | ||
Mean (SD) | 0.89 (0.73) | 0.32 (0.77) |
Range | – 1.0 to 3.1 | – 2.0 to 2.6 |
ADNI visuospatial summary score, ADNI_VS | ||
Mean (SD) | 0.28 (0.57) | 0.05 (0.72) |
Range | – 1.6 to 0.7 | – 2.5 to 0.7 |
