Table 2 Bivariate logistic regression analysis for VTE risk assessment.

From: Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

 

OR

95% CI

 

p value

Pandemic waves

 Other waves

 First wave

1.17

0.86

1.63

0.30

 Second wave

1.37

0.96

1.98

0.09

Age > 70 years

0.94

0.76

1.08

0.28

Sex (female)

0.80

0.58

0.84

< 0.01

Arterial hypertension

1.02

0.82

1.28

0.84

Chronic atrial fibrillation

0.44

0.29

0.65

< 0.01

Cancer

1.37

0.97

1.89

0.06

Dyspnea

1.59

1.32

1.94

< 0.01

Pulmonary infiltrates

1.10

0.84

1.47

0.51

ARDS

2.02

1.69

2.41

< 0.01

Heart rate > 100 bpm

1.44

1.18

1.75

< 0.01

SPB < 90 mmHg

1.06

0.59

1.75

0.83

PaO2/FiO2 ratio < 300

1.79

1.43

2.27

< 0.01

Intensive care unit admission

3.87

3.16

4.71

< 0.01

Lymphocyte < 800/µL

0.99

0.83

1.19

0.93

D-dimer > 1000 ng/mL

4.03

3.35

4.86

< 0.01

CRP > 100 mg/L

1.43

1.20

1.71

< 0.01

Creatinine > 1.5 mg/dL

1.01

0.77

1.30

0.95

Lopinavir/ritonavir

0.83

0.69

1.01

0.06

Remdesivir

1.17

0.82

1.61

0.37

Hydroxychloroquine

1.06

0.84

1.34

0.61

Beta interferon

1.48

1.06

2.01

0.02

Macrolides

0.76

0.63

0.90

< 0.01

Beta-lactams

1.54

1.26

1.89

< 0.01

Corticosteroids

1.98

1.63

2.41

< 0.01

Anakinra

3.28

1.66

5.84

< 0.01

Tocilizumab

2.95

2.41

3.60

< 0.01

Prophylactic LMWH

1.17

0.65

2.33

0.63

  1. ARDS: acute respiratory distress syndrome; CRP: C-reactive protein; LDH: lactate dehydrogenase; LMWH: low molecular weight heparin; PaO2/FiO2: oxygen in arterial blood (PaO2) to the fraction of inspiratory oxygen concentration (FiO2); SBP: systolic blood pressure; VTE: venous thromboembolism