Fig. 6 | Scientific Reports

Fig. 6

From: Genomics of novel influenza A virus (H18N12) in bats, Caribe Colombia

Fig. 6

Molecular analysis and docking of the N protein. (A) A/bat/Peru N11 protein (4K3Y). (B) N protein of A/bat/Colombia/23. (C) Monomer of the N protein of A/bat/Colombia/23 bound to the bat HLA-DR. The contact region (2935.1 ˚A2) between the two proteins is indicated. The Van der Waal energy was 67.8. D. Binding details between residues of the N protein of A/bat/Colombia/23 and bat HLA-DR. (D)The binding of the three mutations Ser361, Ar363, and Lys242 of the hypothetical active site of the N protein with Lys111, pro87, and Val97/Glu98, respectively, with the bat HLA-DR. The image of the 3D model was generated with ChimeraX 1.7.142 (https://www.cgl.ucsf.edu/chimerax/).

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