Fig. 1 | Scientific Reports

Fig. 1

From: Mitigating doxorubicin-induced hepatotoxicity in male rats: The role of aerobic interval training and curcumin supplementation in reducing oxidative stress, endoplasmic reticulum stress and apoptosis

Fig. 1

Schematic illustration of the experimental design. After a five-week pilot study, the animals were acclimatized to a new environment and treadmill for two weeks. Afterward, they were randomly assigned to six groups. Forty-eight hours following the last intervention, they were sacrificed, followed by blood and tissue collection. Some components of the figure were created using images from Servier Medical Art (https://smart.servier.com), which is licensed under a Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/). Abbreviations: AIT, aerobic interval training; DMSO, dimethyl sulfoxide; D, day; CON, control group; Dox, doxorubicin group; Dox-C, doxorubicin + curcumin group; Dox-A, doxorubicin + aerobic interval training group; Dox-AC, doxorubicin + curcumin + aerobic interval training group.

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