Fig. 5 | Scientific Reports

Fig. 5

From: Mitigating doxorubicin-induced hepatotoxicity in male rats: The role of aerobic interval training and curcumin supplementation in reducing oxidative stress, endoplasmic reticulum stress and apoptosis

Fig. 5

Evaluation of apoptosis in the hepatic tissue. (A and B) representative TUNEL staining photomicrographs of the hepatic tissue and the quantitative results for apoptosis in the liver (200 × magnification); (C and D) representative western blot analysis of apoptosis biomarkers and quantitative data in the hepatic tissue. Data are reported as mean ± SD (n = 4/group). * P < 0.05 vs. the CON group; # P < 0.05 vs. the Dox group; $ P < 0.05 vs. the Dox-C group; & P < 0.05 vs. the Dox-A group. Abbreviations: Bax, Bcl2-associated X protein; Bcl-2, B-cell lymphoma 2; CON, control group; Dox, doxorubicin group; Dox-C, doxorubicin + curcumin group; Dox-A, doxorubicin + aerobic interval training group; Dox-AC, doxorubicin + curcumin + aerobic interval training group.

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