Fig. 1 | Scientific Reports

Fig. 1

From: VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway

Fig. 1

VHL and HDAC6 expression in normal mucosal tissues and OSF tissues. (A) The immunohistochemical staining image displayed the VHL and HDAC6 protein levels in both OSF and normal tissues. Scale bars, 50 μm. (B) RT-qPCR results showed VHL and HDAC6 mRNA levels in OSF and normal tissues. (C) The viability of BMFs using an MTT assay. (D) The immunofluorescence staining for α-SMA (green) and DAPI (blue) was captured. Scale bars, 20 μm. (E) WB of VHL and HDAC6 expression in BMFs and fBMFs. *P<0.5, **P<0.01, ***P<0.001.

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