Fig. 4

HDAC6 activates of NF-κB pathway. (A) The effects of overexpression of HDAC6 on the expression of HDAC6, p-IκBα, IκBα, p-p65, p65 were examined by WB analysis. (B) The effects of HDAC6 inhibitor (ACY1215) on the expression of HDAC6, p-IκBα, IκBα, p-p65, p65. *P<0.5, **P<0.01, ***P<0.001.