Fig. 5
From: Hepatic lipid metabolism is altered in Ubiad1+/− mice of both sexes
Lower Ubiad1 mRNA expression affects lipid biosynthetic pathways in male and female mice. (A,B) Heatmap of differentially expressed hepatic genes in Ubiad1+/+ compared to Ubiad1+/- (A) male and (B) female mice (n = 8 per group) as determined by RNA sequencing (FDR < 0.05, FC > 1.5). (C, D) The 10 most significantly different hepatic mRNA expression pathways between Ubiad1+/+ and Ubiad1+/- (C) male and (D) female mice, identified by enrichment analysis. The GO biological process pathway analysis was performed with differentially expressed genes. All the top 10 enriched pathways were increased in Ubiad1+/- mice.
