Fig. 5
From: Impact of LIN7A silencing on U87 cell invasion and its clinical significance in glioblastoma
Immunofluorescence analysis of clinical tumor tissue samples. (A) LIN7A Expression in clinical glioblastoma tissue sample: Fluorescence signals for IDH1R132H (red, right column) and LIN7A protein (green, middle column) were captured and analyzed using ImageJ software. The fluorescence images showed that LIN7A expression was more concentrated in the core region of the tumor compared to the infiltrating area, indicating a potential regional variation in LIN7A expression within the tumor. (B) Quantitative analysis of LIN7A expression across five clinical cases: five clinical tumor tissue samples were analyzed to quantify the expression levels of LIN7A. Statistical analysis confirmed a significant difference in LIN7A expression between the core and infiltrating areas, with the core region showing higher LIN7A levels (*P < 0.01).
