Fig. 2 | Scientific Reports

Fig. 2

From: Enhancing radiation-induced reactive oxygen species generation through mitochondrial transplantation in human glioblastoma

Fig. 2Fig. 2

Proof of concept for allogenic mitochondrial transplantation in human GBM cell lines. Using donor mitochondria from multiple human GBM cells lines (U3020 and U3035; MITO Red), CPPs were used to transplant 100 µg of mitochondria into recipient cells (U3035 (A–E) and U3046 (G–K); MITO Green). Scatter plots of mean staining intensities of native vs. donor mitochondria are presented in panel (F) (U3035-U3020; n = 77) and panel (L) (U3046-3035; n = 139) with a 1.3-fold and threefold increase in donor vs recipient mitochondrial fluorescence intensity in the U3035-U3020 and U3046-U3035 chimera, respectively. All images were acquired at 60X with 100 µm scale bars noted.

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