Fig. 6 | Scientific Reports

Fig. 6

From: Enhancing radiation-induced reactive oxygen species generation through mitochondrial transplantation in human glioblastoma

Fig. 6

Mitochondrial DNA sequence analysis within U3035MT20-3 × chimeras following transplantation. A Circos plot designating the circular mitochondrial DNA of the U3035Mt20-X3 chimeras and the single nucleotide polymorphisms that were either shared variably with U3020 or U3035 mtDNA sequences (grey), completely converted to U3020 (blue), or not expressed in either the donor or recipient lines (orange). Allele frequencies were averaged for the grey SNP’s and combined with the blue SNPs and it was found that the DNA sequence in the 14-day post-transplant U3035Mt20-X3 chimeras was most similar to the donor U3020 line and had only retained a small proportion of the recipient mtDNA sequence.

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