Fig. 2
From: Bistability and bifurcations in HIV-1 infection model with non-monotone responses
The clinical trials were performed on human patients to monitor their viral load under ART. The red dots represent the VL in natural logarithmic numbers and the blue line is the solution of the viral population. The clinical data is obtained from the literature24. It can be seen that VL starts declining once the therapy is initiated, and for some cases, like Human ID:2 there is an immediate response, but the response is slow in human IDs 14, 26, 21, 25, 32 41, and 45. Also, it takes more than 10 weeks for Human IDs: 32, 41, and 45. These results clearly indicate that the efficacy of ARTs are varying for each individual case and cannot be assumed as fixed.
