Table 2 Parameter descriptions and its ranges.
From: Bistability and bifurcations in HIV-1 infection model with non-monotone responses
Parameter | Description | Fitting values | Biological values |
|---|---|---|---|
r | Intrinsic growth rate | 4.38 | 0.03/day47 |
K | Total carrying capacity | \(10^5\) | \(10^5\)cells/mL/day47 |
\(d_T\) | Target cell death rate | 0.01 | 0.01/day21 |
\(\beta\) | Transmission rate | 0.000015 | \(1.5\times 10^{-8}\) mL/day47 |
\(\epsilon\) | Drug efficacy | 0.9 | [0, 1]22 |
a | Saturated constant | 0.1 | 0.1 |
p | New virions production | 2000 | 2000/day47 |
\(\delta\) | Death rate of infected cells | 1 | 1/day22 |
\(c_{1}\) | Virions clearance rate | 23 | 23/day47 |
m | Infected cell elimination rate | 0.00046 | 0.0045 mL/cells/day47 |
\(\eta\) | Immune impairment constant | 0.0012 | 0.1 |
k | Immune saturated constant | 0.052 | – |
c | Immune cell production | 0.000071 | 0.1/ day47 |
b | Death rate | 5 | 2/day22 |
