Table 2 DEPs from tendon biopsies prognostic for DVT at 2 weeks and poor healing outcome at one-year post-surgery.

From: Novel tissue biomarker candidates to predict both deep venous thrombosis and healing outcome after Achilles tendon rupture

 

DVT at 2 weeks

Poor healing outcome at 1 year

OR (95% CI)

p

OR (95% CI)

p

ABI3BP

0.19 (0.04–0.95)

0.042

0.06 (0.01–0.30)

0.001

IGHV4-39*

0.16 (0.03–0.82)

0.028

  

IGKV2-40/IGKV2D-40*

0.14 (0.02–0.77)

0.024

0.24 (0.06–0.98)

0.047

PCYOX1*

0.21 (0.04–1.03)

0.054

0.11 (0.02–0.4)

0.004

STIP1

8.40 (1.40–50.0)

0.019

5.09 (1.20–21.0)

0.026

YWHAQ

0.09 (0.01–0.59)

0.012

  
  1. DVT at 2 weeks (n = 39) and poor healing at 1 year (n = 36). Logistic regression adjusted for patient age. Protein expression dichotomized by median. The proportion of 0-values ≥40% in any group indicated with an asterix (*). Abbreviations: ATRS = Achilles tendon Total Rupture Score, DEP = differentially expressed proteins, DVT = Deep Venous Thrombosis, OR = Odds ratio, 95% CI = 95% confidence intervall for the odds ratios. ABI3BP = Abi family member 3 binding protein, IGHV4-39 = Immunoglobulin heavy variable 4–39, IGKV2-40/IGKV2D-40 = Immunoglobulin kappa variable 2–40/2D-40, PCYOX1 = Prenylcysteine oxidase 1, STIP1 = Stress-induced-phosphoprotein 1, YWHAQ = Tyroseine 3/Tryptophan 5 Monoxygenase activation protein theta.