Fig. 2
From: Treg derived Amphiregulin protects from murine lupus nephritis via tissue reparative effects
Treg derived AREG ameliorates renal fibrosis. (a) Representative Sirius Red stained sections of kidneys from FoxP3cre controls and FoxP3cre x AREGfl/fl mice at 12 months of pristane-induced LN. (b) Quantification of fibrosis at 12 months after LN induction (c) Representative Sirius Red stained sections of kidneys from FoxP3cre and FoxP3cre x AREGfl/fl mice at 15 months of pristane-induced LN. (d) Quantification of fibrosis at 15 months after LN induction. Circles show individual animals and horizontal lines show mean values. Error bars show the standard error of the mean. *** p < 0.001.
