Fig. 1 | Scientific Reports

Fig. 1

From: GOLPH3 promotes calcium oxalate-induced renal injury and fibrosis through Golgi stress-mediated apoptosis and inflammatory responses

Fig. 1

Up-regulation of GOLPH3 expression in renal tissues of patients with kidney stones (A) Representative Tunel staining results of normal renal tissue and renal tissue from patients with renal stones (n = 6). (B, C, E) IHC, qPCR and Western blot analyses of GOLPH3 expression levels in nephrolithiasis patients. (D) Online single-cell sequencing database of snRNA-seq validates GOLPH3 expression levels in normal kidneys versus kidneys of AKI and CKD patients. (F) Representative images (n = 6) of immunofluorescence staining for GOLPH3 (green) and GM130 (red). Data are the mean ± SEM of at least 3 independent experiments. *P < 0.05 , ***P < 0.001 versus NC group.

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