Fig. 3 | Scientific Reports

Fig. 3

From: GOLPH3 promotes calcium oxalate-induced renal injury and fibrosis through Golgi stress-mediated apoptosis and inflammatory responses

Fig. 3

Deposited calcium oxalate stones cause Golgi stress in renal tubular epithelial cells (A) Immunofluorescence staining of Golgi morphological marker GM130 (green) in renal tissue(n = 6). (B, C) The function and structural proteins of Golgi apparatus (GRASP65, ARF4, PI4KIIIβ and MYO18A) and renal fibrosis related proteins (Collagen I, Vimentin, α-SMA) were detected in renal tissues by Western blots and qRT-PCR analysis. Data are the mean ± SEM of at least three independent experiments. **P < 0.01, ****P < 0.0001 versus NC group.

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