Fig. 3

Representative images showing the nuclear morphology of (a) normal cells and (b) cells undergoing mitotic catastrophe. (c) Quantified data for mitotic catastrophe induced in cells treated with IR. 72 h after the final radiation dose (2 Gy), cells were fixed and stained with DAPI. Images of nuclei were acquired using a 40X lens. 100 nuclei were scored. Data are summary of two independent experiments and values are expressed in mean ± SEM. P values determined by two-sided Student’s t-test; **P < 0.01.