Table 2 Baseline characteristics of study participants for the analysis of chronic pancreatitis.

From: Rheumatoid arthritis and risk of pancreatitis: a nationwide cohort study

 

Total

RA status

 

Serological status of RA

 

Non-RA

RA

P-value

SPRA

SNRA

p-value

Participants, No

184,660

138,495

46,165

 

32,185

13,350

 

Sex, Male

41,972 (22.7)

31,479 (22.7)

10,493 (22.7)

 

7,247 (22.1)

3,246 (24.3)

< 0.0001

Age

58.3 ± 9.9

58.3 ± 9.9

58.3 ± 9.9

 

58.5 ± 9.9

57.7 ± 10.0

< 0.0001

40–59

104,852 (56.8)

78,639 (56.8)

26,213 (56.8)

 

18,316 (55.8)

7,897 (59.2)

 

≥ 60

79,808 (43.2)

59,856 (43.2)

19,952 (43.2)

14,499 (44.2)

5,453 (40.9)

Income

 < 25%

41,383 (22.4)

31,011 (22.4)

10,372 (22.5)

0.046

7,399 (22.6)

2,973 (22.3)

0.0002

 Smoking status

   

< 0.0001

  

< 0.0001

 Never

151,098 (81.8)

113,985 (82.3)

37,113 (80.4)

 

26,409 (80.5)

10,704 (80.2)

 

 Former

16,670 (9.03)

12,090 (8.7)

4,580 (9.9)

 

3,036 (9.3)

1,544 (11.6)

 

 Current

16,892 (9.2)

12,420 (9.0)

4,472 (9.7)

 

3,370 (10.3)

1,102 (8.3)

 

 Alcohol consumption

  

< 0.0001

  

< 0.0001

 None

138,681 (75.1)

102,289 (73.9)

36,392 (78.8)

 

26,031 (79.3)

10,361 (77.6)

 

 < 30 g/day

45,979 (24.9)

36,206 (26.1)

9,773 (21.2)

 

6,784 (20.7)

2,989 (22.4)

 

Physical activity

 Regular

37,273 (20.2)

28,825 (20.8)

8,448 (18.3)

< 0.0001

5,850 (17.8)

2,598 (19.5)

< 0.0001

 Body mass index

   

< 0.0001

  

< 0.0001

 < 18.5

5,363 (2.9)

3,594 (2.6)

1,769 (3.8)

 

1,331 (4.1)

438 (3.3)

 

 18.5–23

73,021 (39.5)

53,727 (38.8)

19,294 (41.8)

 

14,027 (42.8)

5,267 (39.5)

 

 23–25

46,110 (25.0)

34,841 (25.2)

11,269 (24.4)

 

8,003 (24.4)

3,266 (24.5)

 

 25–30

53,163 (28.8)

40,917 (29.5)

12,246 (26.5)

 

8,454 (25.8)

3,792 (28.4)

 

 ≥ 30

7,003 (3.8)

5,416 (3.9)

1,587 (3.4)

 

1,000 (3.1)

587 (4.4)

 

 Diabetes mellitus

23,018 (12.5)

17,311 (12.5)

5,707 (12.4)

0.4396

3,949 (12.0)

1,758 (13.2)

< 0.0001

 Hypertension

69,670 (37.7)

51,433 (37.1)

18,237 (39.5)

< 0.0001

12,519 (38.2)

5,718 (42.8)

< 0.0001

 Dyslipidemia

60,416 (32.7)

45,209 (32.6)

15,207 (33.0)

0.2381

10,317 (31.4)

4,890 (36.6)

< 0.0001

 Chronic kidney disease

12,858 (7.0)

9,150 (6.6)

3,708 (8.0)

 

2,473 (7.5)

1,235 (9.3)

 

Lipid profile

 *TG

106.3 (106.0-106.6)

107.2 (107.0-107.8)

103.4 (102.9-103.9)

< 0.0001

102.0 (101.4-102.5)

107.1

(106.2–108.0)

< 0.0001

 Chronic pancreatitis

174 (0.09)

124 (0.09)

50 (0.11)

0.2549

39 (0.12)

11(0.08)

0.2803

 F/U duration

       

 Mean ± SD

5.6 ± 2.3

5.6 ± 2.25

5.5 ± 2.3

< 0.0001

5.5 ± 2.3

5.5 ± 2.2

0.1486

 Median (Q1-Q3)

5.5 (3.7–7.5)

5.5 (3.7–7.5)

5.4 (3.6–7.4)

< 0.0001

5.4 (3.6–7.5)

5.4 (3.6–7.3)

0.0378

  1. RA, Rheumatoid arthritis; SPRA, seropositive rheumatoid arthritis; SNRA, seronegative rheumatoid arthritis; TG, triglyceride; SD, standard deviation.