Fig. 2

Open field and light dark transition testing revealed an anxiety behavioral phenotype in creatine transporter mutated mice. Open field testing results are depicted in A-E (solid bracket) with (A) total distance traveled in meters, (B) distance traveled over time in meters, (C) velocity over time in m/s, (D) number of entries to the center and (E) time in center of the open field. Light dark transition results (dotted bracket) are presented in (F) time to first entry and (G) total time in light. Data are presented as mean + standard deviation. P values of ≤ 0.05 are shown with one (*) asterisk, ≤ 0.01 are shown with two (**), and between 0.0001 and 0.001 are shown with three (***).