Fig. 1

Identification and analyses of sialylation-related genes (SRGs) associated with LUAD survival. (A) The correlation network comprising 26 SRGs associated with LUAD prognosis is presented. The blue and red lines signify negative and positive correlations between the two SRGs, respectively. The purple and green colors within the circles denote that the SRGs function as risk factors and favorable factors, respectively. The magnitude of the circles corresponds to the p-value. (B) The expression differences of 26 prognosis-related SRGs in LUAD and adjacent normal tissues according to the GSCA database. The solid circle represents a significant difference (FDR ≤ 0.05), while the dotted circle represents no significant difference between LUAD and adjacent normal tissues (FDR > 0.05). (C) The single nucleotide variation (SNV) mutation frequency heatmap of 26 SRGs in LUAD. (D) The top 10 mutation profile of prognosis-SRGs. The X-axis is the sample, the Y-axis is the mutated gene, and different colors represent different mutation types.