Fig. 6 | Scientific Reports

Fig. 6

From: AAV-IKV mediated expression of decorin inhibits EMT and fibrosis in a murine model of Glaucoma and AAV-IKV transduction in Non-Human Primates

Fig. 6

Decorin Inhibits Retinal Ganglion Cell Death. Frozen retinal sections stained with BRN3a for quantitation of Retinal ganglion cells (RGCs) in AAV-IKV-TGFβ2CS and AAV-IKV-TGFβ2CS + AAV-IKV-Decorin injected groups as well as uninjected or AAV-IKV-pA injected animals. There was no statistically significant difference in BRN3a staining between uninjected and AAV-IKV-pA injected animals. However, there was a statistically significant greater number of RGCs in the AAV-IKV-TGFβ2CS + AAV-IKV-Decorin injected group relative to AAV-IKV-TGFβ2CS injected animals (p = 0.0322).

Back to article page