Fig. 1
From: Injectable alginate/collagen clindamycin hydrogel for treatment of surgical site infections
Characterization of alginate/collagen hydrogels. (A, B) Scanning electron microscopy (SEM) analysis of (A) collagen hydrogel and (B) alginate/collagen hydrogel. Magnification of 1000× was utilized to observe micro-scale morphological features of the freeze-dried hydrogels. (C) Rheological properties of collagen and alginate/collagen hydrogel were evaluated by storage modulus (G′) of the hydrogels measured over time at 37 °C. (D) average storage modulus (G′) of pre-formed hydrogels evaluated after 120 s at 24 °C, reflecting their stabilized mechanical properties. Error bars indicate ± standard deviation (n = 3). (E, F) In-vitro release kinetics of alginate/collagen hydrogel over a 14 day period. (E) Percentage of clindamycin released. (F) Overall cumulative percentage released. Error bar represents ± SD (n = 4).
