Fig. 4

RRT extract suppresses IL-17 pathway in UVB-induced keratinocytes. (a) Relative mRNA expression levels of IL-17RA, HSP90, TRAF6, IKKγ, MMP1 and MMP3 in keratinocytes. (b) Western blot electrophoresis results and relative proteins expression levels of IL-17RA, c-Fos, and c-Jun in keratinocytes. Statistical analysis involved one-way ANOVA and paired two-tailed t-tests, with significance denoted as ###P < 0.001, ##P < 0.01, #P < 0.05 relative to the control group, and ***P < 0.001, **P < 0.01, *P < 0.05 relative to the control group.