Table 2 Univariate and multivariable analysis for variables selected as predictors for the two-stage scoring system.

From: Development and validation of a risk score for predicting 30-day mortality in patients with ST elevation myocardial infarction

Variables

Univariate analysis

Multivariate analysis 1 a

Multivariate analysis 2 b

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Age group

< 60 years

Ref

 

Ref

 

Ref

 

60–74 years

3.65 (2.44,5.46)

< 0.001

2.96 (1.97,4.46)

< 0.001

2.64 (1.75,3.98)

< 0.001

>=75 years

9.70 (6.47,14.54)

< 0.001

5.67 (3.71,8.67)

< 0.001

4.51 (2.94,6.92)

< 0.001

Female

2.80 (2.18,3.59)

< 0.001

1.74 (1.34,2.25)

< 0.001

1.90 (1.47,2.46)

< 0.001

Systolic blood pressure

≥140 mmHg

Ref

 

Ref

 

Ref

 

90–139 mmHg

1.39 (1.04,1.86)

0.0276

1.52 (1.13,2.04)

0.006

1.46 (1.09,1.96)

0.012

<90 mmHg

6.22 (4.16,9.29)

< 0.001

4.57 (2.97,7.02)

< 0.001

3.59 (2.30,5.61)

< 0.001

Heart rate

<110 beats per minute

Ref

 

Ref

 

Ref

-

≥ 110 beats per minute

5.29 (3.89,7.20)

< 0.001

2.82 (2.04,3.89)

< 0.001

2.15 (1.54,3.01)

< 0.001

Killip class

I

Ref

 

Ref

 

Ref

 

II/III

2.84 (2.15,3.75)

< 0.001

1.85 (1.39,2.46)

< 0.001

1.62 (1.20,2.17)

0.001

IV

7.61 (5.46,10.61)

< 0.001

2.74 (1.89,3.97)

< 0.001

2.15 (1.47,3.14)

< 0.001

Anterior MI

1.80 (1.37,2.35)

< 0.001

1.86 (1.40,2.45)

< 0.001

1.80 (1.36,2.40)

< 0.001

LVEF

≥ 50%

Ref

   

Ref

 

< 50%

3.64 (2.53,5.25)

< 0.001

  

1.73 (1.18,2.53)

0.005

Unmeasured

3.79 (2.73,5.26)

< 0.001

  

2.76 (1.98,3.84)

< 0.001

Serum creatinine

<100 umol/L

Ref

-

  

Ref

 

100–176 umol/L

5.23 (3.94,6.95)

< 0.001

  

2.64 (1.95,3.59)

< 0.001

> 176 µmol/L

11.52 (7.43,17.85)

< 0.001

  

5.05 (3.15,8.10)

< 0.001

  1. MI, myocardial infarction; LVEF, left ventricular ejection fraction.
  2. aMultivariate analysis 1: multivariate analysis for predictor available on early medical contact that included in the FMC stage risk score.
  3. bMultivariate analysis 2: on the basis of multivariate analysis 1, LVEF and serum creatinine were further included in the multivariate analysis.
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