Table 2 Baseline characteristics in relation to poor prognosis six months after acute cerebral infarction.

From: A prospective cohort study on prognostic implications of serum platelet derived microparticles levels in acute cerebral infarction

 

All patients

Poor prognosis

Good prognosis

P value

Age (years)

67.77 ± 7.22

69.32 ± 5.02

67.18 ± 7.82

0.001

Male

400 (64.41%)

122 (65.59%)

278 (62.53%)

0.524

Body mass index (kg/m2)

25.07 ± 1.77

25.34 ± 1.63

24.97 ± 1.81

0.020

Systolic blood pressure (mmHg)

140.53 ± 26.12

138.11 ± 24.63

141.45 ± 26.64

0.155

Diastolic blood pressure (mmHg)

80.03 ± 14.23

79.27 ± 14.74

80.32 ± 14.03

0.413

SmokerAlcohol

335 (53.95%)

104 (55.91%)

231 (53.10%)

0.520

Admission time (hours)

339 (54.43%)

111 (59.68%)

227 (52.18%)

0.086

Blood-collection time (hours)

5.90 (4.60–7.50)

`5.50 (4.70–6.90)

5.20 (4.40–7.20)

0.254

Comorbidity

6.70 (5.50–8.10)

6.20 (5.30–8.00)

6.40 (5.10–8.30)

0.510

 Diabetes mellitus

    

 Hypertension

219 (35.27%)

77 (41.40%)

142 (32.64%)

0.036

 Coronary heart disease

357 (57.49%)

102 (54.84%)

255 (58.62%)

0.252

 Dyslipidemia

202 (32.53%)

66 (35.48%)

136 (31.26%)

0.304

Treatment

317 (51.05%)

101 (54.30%)

216 (49.66%)

0.289

 Thrombolysis

    

 Antiplatelet

193 (64.90%)

51 (27.42%)

142 (32.64%)

0.198

 Statins

403 (64.90%)

116 (62.37%)

287 (65.98%)

0.388

 Anticoagulant

278 (26.09%)

91 (48.92%)

187 (42.99%)

0.173

 GLP-1 agonists

74 (11.92%)

19 (5.38%)

55 (7.36%)

0.392

 SGLT2 inhibitors

37 (5.96%)

15 (8.06%)

22 (5.06%)

0.147

NIHSS score

115 (18.52%)

42 (22.58%)

73 (16.78%)

0.088

 Stroke etiology

13.00 (7.00–16.00)

14.00 (12.00–17.00)

14.00 (12.00–16.00)

0.001

 Small-vessel occlusive

   

0.801

 Large-vessel occlusive

164 (26.41%)

47 (25.27%)

117 (26.90%)

 

 Cardioembolic

198 (31.99%)

56 (30.11%)

142 (32.64%)

 

 Others

125 (20.13%)

41 (22.04%)

84 (19.31%)

 

 Infarction volume (cm3)

123 (19.81%)

42 (22.58%)

92 (21.15%)

 

TOAST subtype

34.60 (23.90–78.00)

38.85 (24.98–91.50)

33.80 (22.80–66.40)

0.046

 Large artery atherosclerosis

   

0.529

 Small artery occlusions

238 (38.33%)

63 (33.87%)

168 (38.62%)

 

 Cardioembolism

305 (49.11%)

97 (52.15%)

212 (48.74%)

 

Infarct location

78 (12.56%)

26 (13.98%)

55 (12.64%)

 

 Anterior circulation infarct

   

0.078

 Posterior circulation infarct

316 (50.89%)

101 (54.30%)

215 (49.43%)

 

 Lacunar infarct

182 (29.31%)

43 (23.12%)

139 (31.95%)

 

Laboratory data

123 (19.81%)

42 (22.58%)

81 (18.62%)

 

 Serum triglycerides levels (mg/dL)

102.23 ± 30.94

   

 Serum total cholesterol levels (mg/dL)

212.93 ± 50.03

102.02 ± 31.77

101.31 ± 30.65

0.918

 Serum HDL-c levels (mg/dL)

49.48 ± 16.18

217.10 ± 41.46

211.34 ± 52.88

0.201

 Serum LDL-c levels (mg/dL)

136.58 ± 42.53

50.60 ± 16.53

49.05 ± 16.04

0.288

 Serum glucose levels (mg/dL)

117.53 ± 42.91

138.04 ± 36.11

136.03 ± 44.75

0.602

 Serum PDMPs levels (ng/L)

26.73 (21.59–33.83)

124.48 ± 40.60

114.88 ± 43.06

0.013

 Platelet count (× 109/L)

239.00 (178.00–302.00)

30.92 (25.40–35.26)

24.94 (19.37–31.61)

 < 0.001

 APTT (s)

28.04 ± 4.58

251.00 (181.75–306.00)

239.00 (178.00–300.00)

0.007

 TT (s)

12.09 ± 3.28

28.34 ± 4.29

27.93 ± 4.69

0.319

 Serum fibrinogen levels (g/L)

4.27 ± 1.55

12.48 ± 4.18

11.95 ± 2.86

0.069

  

4.46 ± 1.45

4.20 ± 1.59

0.066

  1. Data were shown as counts (percentages), means ± standard deviations or medians (upper-lower quartiles) where appropriate. Intergroup comparisons were done using the Chi-square test, Fisher exact test, Student’s t-test or Mann–Whitney test as appropriate. Abbreviations: GLP-1: glucagon-like peptide-1; SLGT 2: sodium-glucose transport protein 2; NIHSS: National Institutes of Health Stroke Scale; HDL-c: high-density-lipoprotein cholesterol; LDL-c: low-density-lipoprotein cholesterol; PDMPs: platelet-derived microparticles; APTT: activated partial thromboplastin time; TT: thrombin time.